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The depression and buy drug carisoprodol with mastercard muscular weaknesswhich is seen in animals under large doses probably arise from affectionof lower parts purchase generic carisoprodol 500mg in thailand of the central nervous system and resemble the conditionknown as collapse more than that of narcosis.the muscular twitching seems to be want to buy soma 350mg tablets online uk entirely buy drug carisoprodol with mastercard independent of thecentral nervous system, for it is not prevented by division of the motornerves. In want to buy carisoprodol in london a pharmacokinetic interaction study in healthy volunteers, no significant effect was observed on the plasma levels of carbamazepine or its active metabolite in patients receiving concomitant azithromycin.cimetidine: there seems some reason to believethat lead is absorbed buy drug carisoprodol with mastercard from the unbroken skin, though it is possible052 the heavy metalsthat some of the metal was carried to the buy drug carisoprodol with mastercard mouth and swallowed whlthe food in the cases on which the statement is founded. The saturation concentrationof solute develops at the interface and decreases with distanceacross the diffusion layer. It is sometimes stated that in aortic regurgitationdigitalis is dangerous owing to its prolonging the diastolic interval andthus allowing more time for the blood to flow back from the aorta. 55). In the course of a few hours. Pulmonary surfactantis a mixture of phospholipids and other associated moleculessecreted by type ii pneumocytes. The individuallydetermined single dose should then be given once buy drug carisoprodol with mastercard or twice daily (eg, at 8 am and buy drug carisoprodol with mastercard 2 pm). Conditions and terms of use applicable to all users of this site. This couple considered the treatment they had chosen an investment in their future relationship. Recent discoveries seem toshow that the ancient egyptians, even thousands of years ago,had probably as fully a developed medical system as we have, withas many if not more specialties. Othersymptoms observed occasionally are blackness of the teeth and tenderness in the gums, which may be due to the acid contained in manyiron preparations; the blackening of the teeth has been supposed to bedue to the tannic acid of the food precipitating the inky black tannateof iron, or to the sulphide of iron being formed by the action of thehydrogen sulphide present in carious teeth. Qa establishes systems buy drug carisoprodol with mastercard for ensuringthe quality of buy drug carisoprodol with mastercard the product. But even in the mostfavorable circumstances little of the metal is absorbed, and in acutepoisoning the symptoms arise from the local irritation and corrosionand only to a smaller extent from the general action of the metal.if the absorption of the metals is slow, their excretion progresseseven more gradually, and repeated qri m j n jq+io+irm \ a +h p j r ap -rnmulation in the tissues and thus to intoxication . Is the buy drug carisoprodol with mastercard drug development teamaware of all possible threats to the project, not only based on all availabledata but also based on theoretical considerations?- the drug development team is capable of reducing or avoiding therisk.- the risk associated with a given project impedes other developmentprojects in the drug buy drug carisoprodol with mastercard portfolio.- the risk is evenly spread over the drug portfolioonce the buy drug carisoprodol with mastercard risk factors of a project have been identified at the start of a project,the team has to share these findings with the functional buy drug carisoprodol with mastercard teams and depart-ments and contractors supporting the drug development project. It causes in animals the samedecrease of consciousness, convulsions and collapse. And some buy drug carisoprodol with mastercard indications of abnormal activity of the bonemarrow cells have been observed in animals supplied with inorganiciron; this may not be the effect of stimulation in the ordinary sense ofthe word, however, for it may pain medication without a prescription be explained by the unusual abundanceiron 645of the materials necessary to their activity. These distended air sacs act like balloons and buoy up the animal so thathe cannot get under water, then he may easily be gathered innets. An animalthat w r as not injured by large quantities given by the mouth, suc-cumbed to quite small buy drug carisoprodol with mastercard doses administered hypodermically. Ip 3 is water-solu-ble and diffuses through the cytoplasm to trigger release of ca +by binding to ligand-gated calcium channels in the limiting mem-branes of internal storage vesicles. The chiefclaim for the introduction of this method is on the groimd that itis much safer than the buy drug carisoprodol with mastercard inhalation method and that it can be moreeasily controlled, since if too much anaesthetic has been taken, buy drug carisoprodol with mastercard order soma 500mg online legally cheap ina moment pure oxygen can be introduced into the want to buy zolpidem 10mg online lungs rhythmically and thus revive the subject.recently, in paris, intramuscular ether anaesthesia has beenplaced in practical operation. Cinchonamine possesses an evenmore marked convulsant action than cinchonidine.the effects of the other alkaloids have not been the subject of much investi-gation, buy drug carisoprodol with mastercard but they seem to differ from quinine chiefly in their effects on the centralnervous system. Patient information about before you start taking it and again each time you get a refill. From these advances flows the requirement formore stability-indicating assay methods as well as increasedemphasis on the impurities in drug substances and products,such as organic volatile impurities and even ordinary impuri-ties derived from raw materials used in production. The contraction is not a tetanus, buta prolonged single twitch, as is shown by the buy drug carisoprodol with mastercard electrical reaction. Even when the alkaliadministered has been neutralized by the gastric juice, the body isrendered more alkaline, because a certain amount of a the carbonate ofthe blood and tissues is spared, which would normally have been usedto neutralize the hydrochloric acid before it could be reabsorbed. At first stitntdation of the buy drug carisoprodol with mastercard respiratory and vasomotorcentres in the meduha, followed by depression. The fresh glandmay be administered raw or sughtly broiled. When administered by the mouth it is excreted in theurine partly as salicin, partly as saligenin or salicyl alcohol, and partlyas salicylic and salicyluric acids.acetylsalicylic add, or aspirin, passes through the stomach unchangedand is free from the gastric effects of salicylic acid and the salicylates.it is partially decomposed into salicylic acid in the bowel, but some ofit appears to be buy drug carisoprodol with mastercard absorbed in its original form. Studies on the induction by furosemide of chromosomal aberrations in micewere inconclusive. This contraction of the vessels is due to local actionupon the vasoconstrictor endings.these symptoms differ from those produced by digitalis, asthey are of exceedingly short duration; also because the vascxilareffect is infinitely more marked than that on the heart muscleand is the chief feature in the rise of blood pressure with buy drug carisoprodol with mastercard suprarenal extract. Once sufficient data have been gathered to agree ona therapeutic strategy, the drug under development has still to be tested intherapeutic confirmatory trials with larger and diverse groups of patients. What are the effects of phosphodiesterase inhibitors in men with erectile dysfunction of any cause? Most patients reported erectile dysfunction of at least 1 yearin duration. Propecia, you will gradually lose any hair that you have gained within 12 months of stopping the propecia program &8211; in addition to normal hair loss resuming. These symptoms are very similar to those order pain meds from canada observed injaundice in hmnan beings.when given by the mouth, they increase the peristalsis of theintestines and the absorption of fats, and decrease intestinalputrefaction. The dmf system applies to activeas well as to inactive pharmaceutical ingredients and to packaging materials. Buy drug carisoprodol with mastercard the importance of corporal smooth muscle tone in the control of erection. Thyroid dysfunction has been associated with alteredmetabolism of some drugs and of some endogenous compoundsas well. It has carisoprodol 500mg prescription bottle also beenused in the form of an ointment to destroy pediculi on the body.picrotoxinum (b.), a neutral principle, soluble in alcohol and onlysughtly in water, obtained from anamirta panniculata which is used extensively in india as a fish poison.0010.003 g. Undergoing dilatation under the action of cgmp more blood is supplied to the erectile organs which are corpora cavernosa in case of males. A frog may remain motionless for days, and finally recoverwhen the poison has been excreted.in man we have practically the same general symptoms as inanimals, accompanied in the beginning by a feeling of fulness inthe head with headache, by an increased secretion of sweat, tears,urine, and later by a blueness of the skin when the muscles ofrespiration have been paralyzed.with small doses, in all animals, the circulation and nervous system remain practically unaffected. Dose, 30-60 grs.the organic adds buy drug carisoprodol with mastercard have a much less marked buy drug carisoprodol with mastercard local action than the inorganic,causing little or no corrosion unless when applied to mucous surfaces in veryconcentrated form. The boundary layer betweena particle and air is commonly referred to as a surface, whereasthe boundary layer between a particle and a liquid or solid iscommonly referred to as an interface. Itseems probable that this acts merely as a mechanical support and thatatropine 331the same result would follow soma disease the application of simple adhesive plasterwithout atropine.to paralyze the cardiac inhibitory terminations. On account of their depressant action onsmooth muscle carisoprodol 500mg prescription for fibres, they are given in asthmatic attacks, to relieve the supposed spasm of the smaller bronchi.ethyl nitrite in the form of sweet spirits of nitre, has beenused for many years to increase the flow of urine and sweat.it has but little action on the urine, but under favorable conditionsit may buy drug carisoprodol with mastercard well produce sweating by dilating the cutaneous bloodvessels.amylis nitris (u.) (q hu no,) yellow, volatue, liquid with astrong odor of banana and a burning taste, soluble in alcohol and ether.it contains 80 buy drug carisoprodol with mastercard per cent, of absolute amyl nitrite, the balance being composedof byproducts. Since colchicine acts but slowly in warmbloodedanimals, and almost not at all in the coldblooded, unless ithas been previously oxidized, it is believed that the action ofcolchicine is due to its oxidation product.colchiceine also present in colchicum has the same actionas colchicine, but in a milder degree.summary of group kctlotx.— intense cheapest generic soma 500mg online in usa irritation of thegastro'intestinal tract and kidneys. Quinine possesses some irritant action which betrays itself indiscomfort in the stomach and eructation after large and repeated dosesby the mouth, and by pain and tenderness when it is injected sub-cutaneously; but this drawback is not of so much importance as inthe case of many other drugs.iarge doses of quinine produce some confusion and depression witha sense of fulness and heaviness in the head from their action on thecerebrum, and this is sometimes accompanied by uncertain gait andslow pulse. (1530 buy drug carisoprodol with mastercard grains.)average (u.) i buy soma pills online g.(3) order soma 500mg in london miscelliueous division.paraldehydiim (u.), colorless liquid with a disagreeable odorand burning taste, soluble in alcohol and ether, soluble in 8 parts of water.dose : for these objects, solutions of the alkaloidal salts aregenerally applied to the conjunctiva, when enough of the alkaloidpasses into the eye by a process of imbibition to produce marked localeffects without affecting more distant organs. The fetus is most sensitive to adversedrug effects buy drug carisoprodol with mastercard during the first trimester.

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(after lewin and guillery.)when complete dilatation is purchase soma 500mg online with mastercard attained, the pupil ceases to contractin bright light, as the impulses descending from the central nervoussystem are prevented from reaching the muscle, although the rest ofthe reflex arc is intact. The oil of sandalwood seems to produceless irritation than those of cubeb and copaiba.the medical administration of these bodies is not infrequentlyaccompanied by buy drug carisoprodol with mastercard pain in the stomach with where to buy soma 500mg online with prescription dyspeptic and buy drug carisoprodol with mastercard entericsymptoms, and also by pain in the back, over the bladderand in the urethra after micturition. Ttesolution is often made up with b' per cent, of sodium chloride or urea. Oil of wintergreen is more irritantlocally than salicylic add because it possesses in carisoprodol 500mg online usa addition to itscharacteristic action, the irritant where to purchase alprazolam 2mg online with mastercard effect of all volatile oils. Complete bloodlessness of a part maythus be elicited without alteration of the general blood-pressure, andin fact without any appreciable effect upon other parts of the body.this local ischemia has been largely employed to allow of bloodlessoperations on the eye and to remove congestion of the conjunctivafrom various causes. Of the substitutes for codliver oil, lipanin has little taste and is generally buy drug carisoprodol with mastercard takenreadily. Animals which areimmune to ricin are not more resistant to the action of abrin than others,because the two poisons form different antitoxins. Most of the patients inwhom these events have been reported had pre-existing cardiovascular risk buy drug carisoprodol with mastercard factors. Thus, the light-reflex is preserved, thepupil contracting in bright light and dilating further in the dark; anumber of drugs which have little or no effect after atropine, contractthe cocainized pupil (pilocarpine, muscarine, physostigmine), whileatropine dilates it still further, and cocaine produces some buy drug carisoprodol with mastercard dilatationafter the full atropine action buy drug carisoprodol with mastercard has been elicited. As visual obser-vation alone under ordinary light is a poor test of clarity, a mi-croscope light should be projected through a diaphragm intothe solution. Oz.reduced iron and the four carbonate preparations are used exclusively inthe treatment of anaemia. On the other hand it has little or no irritantaction on the mouth and throat, and is digested and rendered harmless in thestomach. Sops also describe in detail the procedures that are necessary for theconduct of nonclinical safety studies. (note thatthe abbreviation ed 50 has a different meaning in this context fromits meaning in relation to graded dose-effect curves, described inprevious text). Buy drug carisoprodol with mastercard the respiration is quicker and deeper after smallquantities, but after lethal doses becomes slow and weak, and finally ceases.periodic respiration often occurs before the final standstill, a series of deepdyspnceic movements alternating buy drug carisoprodol with mastercard with several shallow, insufficient ones. The soma 500mg prescription los angeles symptoms buy drug carisoprodol with mastercard are those of transient stimulation andsubsequent buy soma online india depression of the central nervous system and heart. Drug-drug interactions antacids ciprofloxacin has been shown to be active against most isolates of the following bacteria, both in vitro and in buy drug carisoprodol with mastercard clinical infections ciprofloxacin [see soma usa indications]. This it may do both by producing a dilatation of the splanchnic blood vessels and by decreasing the bulkof blood through watery evacuations.the use of purgatives is indicated in all cases when the intestineis to be emptied, as after poisoning from drugs and from foodproducts, or buy drug carisoprodol with mastercard when there is infection of the intestines, as in typhoidfever, or autointoxication due to fermentation or putrefactivechanges in the intestinal contents.170 local organic drugs.they should not be used when there is severe inflammation of theintestines, and only with caution during pregnancy. Comprehensive treatments of all as-pects of pharmaceutical product stability have been publishedby connorset al.1, carstensen2and more recently by allen.3this chapter will outline the appropriate steps from prefor-mulation to drug approval to assure that the pharmaceuticalproduct developed is stable. Hemodialysis (performed between 24 and 30 hours post-dose) contributed negligibly to tadalafil or metabolite elimination. For this pur-pose it is prescribed in very much smaller quantities than those neces-sary to produce emesis. Sildenafil citrate is a white to off-white crystalline powder with a solubility of 3.5 mg/ml inwater and a buy drug carisoprodol with mastercard molecular weight of 666. Behavioural evidence for central d-2 dopamine receptor agonistic effect by some 2-(fluorohydroxyphenyl)ethylamines. Theammonia is probably augmented, for a considerable amount of lacticacid has been obtained from the urine. It mustbe distinctly understood that the following symptoms betoken a gravecondition of poisoning.in the second stage the buy drug carisoprodol with mastercard symptoms are due to excessive inhibitoryactivity, buy drug carisoprodol with mastercard while the direct cardiac action is less developed. The failure rate during regulatory review by theauthorities is 25 % . This is called buy generic tramadol online aclinicalhold. The balance is composed of a variety of closely allied bodies,of which the principals are quinidine, cinchonine and cinchonidine.tinctura cinchona (u. The following numbers do not provide medical advice, but in the us you may report side effects to the food and drug administration (fda) at 1-800-fda-1088. Ask your doctor, nurse, or pharmacist any questions that you may have about this medicine. 55) and become regular;the ventricle now receives no impulses from the auricle, but hasdeveloped its own spontaneous regular rhythm. Carcinogenesis, mutagenesis, buy drug carisoprodol with mastercard impairment buy cheap soma 350mg tablets online of fertilitysildenafil was not carcinogenic when administered to rats for 24 months at a dose resulting intotal systemic drug exposure (aucs) for unbound sildenafil and its major metabolite of 29- and42-times, for male and female rats, respectively, the exposures observed in human males giventhe maximum recommended human dose (mrhd) of 100 mg. Maca is effective in eliminating hot flashes and moderating mood swings, which makes sense given its function in regulating hormone levels. On a global improvement question, 83% ofpatients reported improved erections on tablet versus 12% on placebo. The administration ofpotassium iodide does not accelerate the elimination of mercury. Brand online pharmacy, no prior prescription or health insurance needed. Until further experience is obtained, nospecific treatment for an overdose with finasteride can be recommended. Injected; the respiratory movements are much buy drug carisoprodol with mastercard larger. The assayneeds to be specific for the target under study, sufficiently sensitive and reproducible and adapted for use in highthroughput automated systems.

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Discontinue buy drug carisoprodol with mastercard cipro where to buy alprazolam 2mg online legitimate xr immediately at the first signs or symptoms of any serious adverse reaction. Some of the iodide doesnot appear in the urine, however, and its fate in the body has not beenvery clearly traced. The best known of such nitrates is the so-called nitroglycerin, which isreally the trinitrate of glycerin,and is broken up by alkalies into a mixture of nitrates and nitrites.the nitrates have practically no action in the small quantities given,so that almost all the effects of nitroglycerin are due to the nitrite388 substances acting after absorptionformed. While making the over your ed episode i wonder if the writers really wanted him to have red hair. The normal pendulum movements continue afterward. This irritant action also occurs in thekidneys, where they are excreted partly changed.the untoward effects buy drug carisoprodol with mastercard which are sometimes observed areexcessive sweating, skin eruptions, chills, digestive troubles, irritation of the kidneys, buzzing in the ears, disturbances of vision,cyanosis and collapse. It has been employed in somecases of shock to raise the blood-pressure. The major polar groups found in most surfactants may be divided as follows:anionic, cationic, amphoteric, and nonionic. It is likely that buy drug carisoprodol with mastercard change will continue to occur at afaster buy soma onlin pace in the smaller and more opportunistic biotechnol-ogy areas than within large pharma partners.clinicians and clinical scientists often lead the discovery buy drug carisoprodol with mastercard ofnew uses for drugs and new directions for research based onobservations made in the clinical setting. Tremendous increase in the flow of urine in dropsicalconditions due to uncompensated heart. When injected into a vein, sparteine induces less increasein the arterial tension than coniine, probably because the contraction of thevessels is counterbalanced by the weakness of the heart. All three preparations are prescribed in powderor tablets, in the buy drug carisoprodol with mastercard same dose as quinine.a famous preparation of quinine is warburg's tincture, which has been exten-sively used m india in the treatment of malaria. It is found, however, thatatropine does not remove the effects of nicotine on the rabbit's eye,which would seem to indicate an action on the muscular fibres of theiris. — the caustic alkalies are used externally to alimited extent to remove growths, such as buy drug carisoprodol with mastercard warts, valium 10mg online pharmacy canada from the skin. Some diseases that cause impotence may be serious, even life-threatening. Overuse ofantibiotics will lead to a future where infectious disease hasthe same impact as in in the pre-antibiotic era. Arsenic is contraindicated in cases of irritation ofthe stomach and bow r el, and is generally avoided during buy drug carisoprodol with mastercard acute fever,except in malaria.if symptoms of chronic poisoning begin to assert themselves, thedrug must be discontinued at once. The contents ofthe annual report are specified in the regulations. These take the form oftwo types: if you take the medication daily, take it at the same time each day. The thiosulphate isapparently oxidized with greater difficulty, for walko found 30-50 per cent,eliminated by the kidneys unaltered.much larger quantities are required to poison animals when given by themouth than when injected subcutaneously, because the buy drug carisoprodol with mastercard salt is changed to theharmless sulphate before it reaches the blood. Cipro xr is not indicated for pediatric patients. However, there are no clinically relevant examples ofchanges in drug disposition or effects that can be clearly ascribedto changes in plasma protein soma 350mg prescription ny binding (benet hoener, 2002).the idea that if a drug is displaced from plasma proteins it wouldincrease the unbound drug concentration and buy drug carisoprodol with mastercard increase the drugeffect and, perhaps, produce toxicity seems a simple and obviousmechanism. It is possible buy drug carisoprodol with mastercard that colchicum improves where to buy soma 500mg online with prescription some cases ofgout by its analgesic power, or it may buy drug carisoprodol with mastercard be that the good effectssometimes observed come from some influence on the generalmetabolism.colchici connus (u.) and colchici semen (u.), the rootand seeds of colchicum autunmale or meadow saffron, a plant growing ineurope and north africa. Nowadays, buy drug carisoprodol with mastercard we have much safer drugs for these purposesand only employ as flavoring agents, preparations of wild cherryand bitter buy drug carisoprodol with mastercard almonds which contain traces of hydrocyanic add.group op carbon monoxide. Salicylic acid is now seldom given,sodium salicylate having supplanted buy soma 500mg in the uk it. Bioavailability of finasteride was not affected byfood.distributionmean steady-state volume of distribution was 76 liters (range, 44-96 liters; n=15). A mixture of 5 per cent, carbonic acidcarbonic acid 573in air causes acceleration and deepening of the respiration without furtherchanges.carbonic acid in excess acts as a poison to other organs besides the centralnervous system and the heart, although this effect is not seen in mammals.frog's muscle loses its irritability rapidly, the ciliated epithelium ceases move-ment and the motor nerves, order carisoprodol online ireland after a short period of increased excitability, areparalyzed by exposure to an atmosphere of carbonic acid. The crude preparations of veratrum viride and veratrum album were formerly employed buy drug carisoprodol with mastercard forthe same purposes as those of aconite, i., to reduce fever andlower the rate of heart beat, but the same objections applyto such a use as to that of aconite.veratrina (u.) a mixture of alkaloids prepared from sabadillaseeds or asagraea officinalis (u.) or buy drug carisoprodol with mastercard schoenocaulon officinale (b.), including crystalline veratrine or cevadine, amorphous veratrine or veratridineand sabadilline or cevadhiine. Such,and partly as an oxidation product.when this drug is given in large doses to an ordinary individual,or in moderate doses to a very susceptible human b6ing, varioussymptoms called imtoward effects occur. Sops and opms are extensively used in chemicaland pharmaceutical development and in major units the buy drug carisoprodol with mastercard number of sopsgoverning pharmaceutical development and manufacturing activities may beas high as buy carisoprodol cheap online several hundred to a thousand documents. May improve want to buy soma 350mg mastercard a man's sexual abilities, but there carisoprodol 500mg may also be a profound cost where to buy soma 350mg involved. Uk tesco, secure purchase, extra comps and discounts, fast delivery. After oraladministration, vardenafil is excreted asmetabolites predominantly in the feces(approximately 91-95% of administered oral dose) and to a lesser extent in the urine(approximately 2-6% of administered buy drug carisoprodol with mastercard oral dose). If swallowediron 641in large quantities, they cause pain and uneasiness in the stomach,nausea, vomiting and often purging, with all the ordinary symptomsof acute gastrointestinal irritation. Same appearances following its injection in the frog as afterdigitalin and veratrine, while in mammals the rhythm is slow even afterparalysis of the inhibitory mechanism.curara i an extract of varying constitution and strength and the active con-stituents are freely soluble in acidulated water, buy drug carisoprodol with mastercard attempts buy drug carisoprodol with mastercard have been made touse curara in various forms of convulsive spasms, but without adequate results. News offers dozens of rss feeds you can read in my yahoo! Although good manufacturing practices (gmp) regulations were developedto steer the manufacturing of drugs intended for the market, they are alsoapplied to candidate drugs during development. The volume of distribution may be overestimated inobese patients if based on body weight and the drug does not enterfatty tissues well, as is the case with digoxin. — the aqueous solutions of ammonia are compara-tively rarely employed, although the strong solution has been advisedas a vesicant in cases of renal disease, in which cantharides is contra-indicated. After administration through any one of the channels of absorption, as the subcutaneous tissues, gastrointestinal tract,rectum and lungs. Other alkaloids (e., nicotine, physostig-mine), which apparently act on the samepoint as cur ara b ut in theo pposite direc tion, cause fibrillary twitching of the muscle fibres; butafter c urara, nicotine apd physostigmine are i neffective unless in verylarge quantities and, on the other hand, the effects of a small amountof buy drug carisoprodol with mastercard curara may be removed by those drugs.the second group of efferent nerve fibres are known as the autonomicsyst em and end in a "yfork ground gnnglkn cells from these ganglioncells, fibres proceed which again terminate in a network over a buy drug carisoprodol with mastercard numberof organs and muscles, which are not generally under the control the will and are known as the vegetative organs. The great news is that they are open all year round so pop in and have a chat with them while it’s  quiet. The fate of the other antipyreticsresembles that of antifebrine, the quinoline discount soma derivatives undergoing a partialoxidation resulting in a body analogous buy drug carisoprodol with mastercard to paramidophenol, while the phene-tidine compounds are partially decomposed and appear in the urine as glycu-ronates of phenetidine. Visiting Artist Application. Thefrequency of excitatory spikes on the eeg after the administrationof etomidate is greater than with thiopental. It is absorbed rapidly and cir-culates in the blood longer than the arsenites, which are taken up by the tissuesrapidly and thus can exert only a transient action on parasites living in theplasma.

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