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The protocol should definesample collection times and techniques to collect the biologi-cal fluid. Not every activity in valium 10mg prescription korea drug rd has to take place withinthe drug rd organisation, but every activity that is outsourced has to befinanced. It seems to have little or no irri-tant action on the alimentary canal or kidneys in animals, and is excretedin part by the kidneys as phenol double sulphate, in part unchanged by thelungs.santesson states that haemorrhages occur very frequently in fatal poisoningin man, and found the same result in experiments on rabbits; he ascribes itto fatty degeneration of the cheapest generic valium 5mg in thailand arterial walls, which was well-marked in mostof his experiments. This was greater the longer the etherwas administered. If the administration of mercury be stillpersisted in, the teeth become loose and fall out, gangrene of the gums,lips and throat, and necrosis of part or even of the whole jaw may follow.the milder forms of stomatitis and salivation are observed in a largeproportion of cases of syphilis treated with mercury, according to someauthors in 30 per cent, or more. The corresponding glycerite and elixir arequite superfluous.iron is contained in many mineral waters, which are therefore advised incases of anaemia. The results obtained since its introduction byroux have been astounding. A sensation of numbness due todepression of the sensory nerves follows these symptoms ofprimary stimulation.the pidse at first is slow and full, due to the peculiar action ofveratrine upon the heart muscle, and to the rise of bloodpressure incident to the stimulant .effect on buy cheap zolpidem 10mg with american express the vasomotor centre.after this primary stimulation, the vasomotor and respiratorycentres become depressed and the subject becomes pale, hispulse feeble and irregular. In some lower animals such asfrogs, and occasionally in human beings with an idiosyncrasytowards morphine, it produces excitement and actual convulsionsby stimulation of the cord. Propranolol, a nonselective (3-adrenoceptor blocker, is a use-ful antihypertensive agent because it reduces cardiac outputand probably vascular resistance as well. Emetics, such as apomorphine,have been used occasionally to cause pressure on other abdominalorgans, e., on the gall-bladder in order to dislodge a calculus valium 5mg prescription philippines or plugof mucus in the ductus choledochus, valium 10mg prescription korea but valium 10mg prescription korea this treatment is not to beadvised, owing to the risk of rupture of the gall-bladder. These observationswere confirmed by a number of authors, who removed the thyroidsfrom animals, and found a cachexia appear in them. When the heart is abnormally weak,we give digitalis to increase its strength, and when the kidneys arenot excreting a sufficient amount of urine, we stimulate themwith some of what is the half life of soma the various diuretics. Are generallyregarded as less irritant than the chlorides, but are less frequently usedand less well known.the least corrosive of the salts of the metals are those formed withthe slowly dissociated organic acids, such as the acetates, tartrates orcitrates. Phosphodiesterase - 5 inhibitors (pde - 5 inhibitors), taken at least one hour before planning to have sexual activity. The expert working group (ewg) that develops new (harmonised)guidelines and of which the members are appointed by valium 10mg prescription korea the ich steeringcommittee; the implementation working group (iwg) that facilitates the implementation of the guidelines in valium 10mg prescription korea the ich member states; and the informal working group that develops concept papers on scientifictopics which may be the subject of future harmonisation. A drug can be affected chemi-cally by radiation of a particular wavelength only if it absorbsradiation at that wavelength and the energy exceeds a thresh-old. The reduction insurface area and in surface free energy accompanying flocculation or coagulation is small, because irregular solid particles arerigid and only touch at a valium 10mg prescription korea few points upon aggregation. If valium 5mg prescription mexico how atropine be injected, stimulationcauses no increase in the valium 10mg prescription korea secretion, and atropine, therefore, seems toparalyze some part of the peripheral secretory where to buy valium online legitimate apparatus. Revalidation of bioequivalence may be neededfor major changes in the manufacturing process, whereas smallchanges may not raise significant bioavailability concerns.in situations involving minor changes in the manufacturingprocess, comparative dissolution testing of the original andreformulated product provides adequate documentation diazepam 10mg cheap prices of con-tinued product quality, if the resulting dissolution profiles aresimilar. Among the many such, may be cited diphtheria, tetanus,typhoid fever, bubonic plague, cholera, etc.some of these toxines produce a pharmacological action notvery different from that of some wellknown drugs. The retina is unprotected from bright light andthis often gives rise to pain and discomfort in the eyes and headache.besides the dilatation of the pupil, a further result of the applica-tion of valium 10mg prescription korea atropine to the eye is the paralysis of the accommodation. As a result of this binding the normal function of the protein target ismodified or inhibited, which may lead to a (favourable) biological response.examples of such hypothesised links between target and purchase generic diazepam 5mg online india disease are the leptinreceptor in obesity [3], the lowdensity lipoprotein receptor in atherosclerosis[4], complement receptors in inflammation [5] and interleukin4 in allergicdiseases [6]. This point was well made byjurgen drewes21when he wrote, “it is, however, by buy drug diazepam 10mg tablets online no meanscertain to what extent molecular diversity, valium 10mg prescription korea as viewed by chem-ists and as calculated by structural descriptors, resembles di-versity as ‘seen’ by a biological target molecule.”collections of compounds can be designed valium 10mg prescription korea to be “drug-like”in that they have favorable physicochemical properties in com-mon with known drugs. The results show that the film coat-ing does not impart the degree of acid stability that the valium 10mg prescription korea entericcoating does when the tablets are administered immediately af-ter food in a typical clinical situation. These materi-als must be inspected and tested against rigid specificationsto ensure that they meet predetermined functional standards.this includes evaluation of compatibility of the product withthe packaging materials. Zovirax is used for treating chickenpox and treating or suppressing genital herpes infections. The fatal is valium a prescription drug dose in man valium 10mg prescription korea is believed to be about0.08 g. (1j— 5 grs.) per day in 10 valium 10mg prescription korea per cent, solution.a number of other arsenic compounds similar to atoxyl valium 10mg prescription korea have been testedrecently in trypanosomiasis and other diseases. However, biologicalscientists have played an equally essential role in originatingmeaningful screening and testing valium 10mg prescription korea models and in the overallevaluation of new agents. It has induced fatal poisoning in the dose of 0. Attention to heterosexual imagery as eliciting stimuli for autonomic sexual arousal in males. Each facility’sinstitutional review board (irb) must approve the protocol(s)conducted under the ind.although the trial may proceed, reviewers at the fda mayplace a “clinical hold” on valium 10mg prescription korea the valium 10mg prescription korea trial at any time. There are 4 stages of a valium 10mg prescription korea cold sore. The indicationsare for a mild and prolonged action such as can be induced by smalldoses of ipecacuanha, antimony and similar bodies, rather than for themore transient effect of apomorphine, but the latter has been advisedby some valium 10mg prescription korea authorities.ipecacuanha (cephselis ipecacuanha) has long been used for itsemetic and expectorant virtues, and until recently was believed tocontain only one alkaloid, emetine. Stage ii excitement: thus, genetic polymorphisms of these enzymes, bysignificantly influencing phase i drug metabolism, can alter their succinylcholine is metabolized only half as rapidly in persons withgenetically determined deficiency in pseudocholinesterase (nowgenerally referred to as butyrylcholinesterase [bche]) as in per-sons with normally functioning enzyme. Patients taking indinavir,saquinavir, atazanavir or other potent cyp3a4 inhibitors such cheapest generic diazepam 5mg online with mastercard as clarithromycin,ketoconazole 400 mg daily, or itraconazole400 mg daily should not exceed a dose of2.5 mg once daily. Surfaceactive agents also may play an important role in determiningwhether an oil-in-water (o/w) or a water-in-oil (w/o) emulsionpreferentially survives the shearing action.once the process of dispersion begins there develops simultaneously a tendency for the system to revert to an energetically more stable state, manifested by flocculation, coalescence,sedimentation, crystal growth, and caking phenomena. In fig. Quinic acid, a substance present in the barkof dnchona and many other trees is said to decrease valium 10mg prescription korea the formation of uric add and itself is transformed and excreted as hippuric add. Instead of a slow pulse and lessened tensionof the arteries, acceleration and increased blood-pressure are thenobserved. Answers to specific problems may not apply to everyone. In these “emulsions within emulsions,” any drug present in the innermost phase must now crosstwo phase boundaries to reach the external, continuous phase.it is important for pharmacists to valium 10mg prescription korea know the type of emulsion they have prepared or are dealing valium 10mg prescription korea with, because this canaffect its properties and performance. (60-120grs.) doses. Among its where to purchase valium 5mg online with paypal derivatives the most satisfactory antipyretics are thosein which the hydrogen of the hydroxy i is substituted by alky i, while an acidradicle is added to the amido-radicle. Avoid reaching the cream into the eyes and healthy parts of the skin. Iti04 • constitutional organic drugs.may act in such cases purely as a local irritant in stimulatingthe processes of repair, or it may influence the causative agent.it is used especially in the form of dover's powders to producesweating in acute colds. In the pastmost drugs were discovered either by identification of valium 10mg prescription korea the ac-tive ingredient from traditional remedies or by serendipitousdiscovery. Apply Zovirax Cold Sore Cream now and you could speed the process by days.

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In most cases the effects of the lastgroup are made up of a valium 10mg prescription korea mixture of astringent low cost ativan 2mg and irritant action.the insoluble salts come into less intimate contact with the tissues,and have much less effect; but many of them are slowly taken upand may then act as irritants or astringents.the insoluble preparations of mercury tend to irritate and corrodethe surfaces to which they are applied, but the insoluble salts of theother metals are generally astringent. Abortion, which issaid to have been seen after quinine, is probably due to bothirritation of the gastrointestinal tract and also to a stimulantaction on the smooth muscles of the uterus, corresponding to themuscular stimulation observed in valium 10mg prescription korea frogs.the other alkaloids of cinchona possess an action closelyresembling that of quinine, except that they have some tendencyto produce increased reflex irritability and convulsions. The total nitrogen is somewhat increased from thelarge amount of ammonia, but the urea is slightly decreased. Examplesdiscussed in this book include: at present it is used to a limited extent as an emetic, but isslow in action and induces greater depression and more prolongednausea than the other drugs which are prescribed for this purpose,such as apomorphine, ipecacuanha, or sulphate of copper. Although a causal relationship has not been established, consideration should be given to the frequency of monitoring prothrombin time when azithromycin is used in patients receiving coumarin-type oral anticoagulants.cyclosporin: for example, water moleculesare hydrogen-bonded to the hydroxyl groups of polyvinyl alcohol, hydroxyl groups, and ether linkages of polysaccharides,ether linkages of polyethylene oxide or peg, amide groups ofpolypeptides and povidone, and carboxylate groups of anionicpolyelectrolytes. If this irritation of the secretorycells be long continued, it sets up a buy drug diazepam 10mg online with prescription secondary inflammation of theinterstitial tissue, and cirrhosis of the kidney results.the circulation is differently affected by different metals. The solutions of how can i buy ultram the carbonates are much soma carisoprodol online lesscorrosive than those of the hydrates, and induce actual lesion of theskin valium 10mg prescription korea only under exceptional circumstances, such as very prolongedapplication.ip the mouth the hydrates and carbonates have a characteristic"alkaline" taste, and dissolve the superficial layers of valium 10mg prescription korea the liningmembrane and the valium 10mg prescription korea mucus of the secretions. This is dueto beginning exhaustion of some cardiac fibres. Absolutely puredigitized by vjooq lcnicotine group 305nicotine has comparatively little odor, but it decomposes when kept,becomes dark colored, and acquires the characteristic odor of tobacco.nicotine is valium 10mg prescription korea also found in the pituri plant (duboisia hopwoodii),the valium 10mg prescription korea leaves of which are used by the australian natives in the same wayas tobacco by the civilized races.lobeline (c18h23no2), an alkaloid obtained from lobelia inflata orindian tobacco, and cytwine, (c11h14n2o), the alkaloid of laburnum(cytisus laburnum), gorse and other plants, resemble nicotine veryclosely in action, and another body of the same type of action valium 10mg prescription korea is theartificial quaternary ammonium base, methylhordenine.these alkaloids act chiefly on the ce ntral nervous system, t he sym-pathetic ganglia, and the pymif? For example, the half-life of diazepamincreases with patient age. Valium 10mg prescription korea tom lue, md, in which a minimum of testing is performed. Respiratory effectsall volatile anesthetics possess varying degrees of bronchodilatingproperties, an effect of value in patients with active wheezing purchase tramadol 100mg online with paypal andin status asthmaticus. The mouth and throatare stained yellow, and the stomach and intestine exhibit the usual appearanceof violent corrosive poisoning.the general action of chromic preparations may be elicited in animals bysubcutaneous or intravenous injection, or by the administration of smallerquantities by the mouth. Forexample, if the cause of a disease has been identified as valium 10mg prescription korea aninfection by a microorganism, a search can be undertaken foran agent that valium 10mg prescription korea will prevent or cure the infection. It hasalso been stated, and denied, that the mental energy is reduced by theuse of tobacco, and an attempt has been made to demonstrate this bymeasuring the amount of work done with and without tobacco; butinvestigators are not agreed on the results, which probably dependlargely upon the individual. Thussyphilis and several of the exanthemata are generally acceptednot to recur during the lifetime of an individual. These antibiotics arechemically modified derivatives of valium 10mg prescription korea biosynthetically producedantibiotics, which possess improved spectra of action or otheradvantageous chemical and biological properties. What I experience and learned through ONE Conference is how precious your youth group is. Effects of psychotropic drugs on human erection and ejaculation. It is probably cost of xanax without insurance due to directaction on the retinal cells, as it is more marked if strychnineis injected subcutaneously in the neighborhood of the eye,and the eflfect is seen best on the one near where the injectionhas valium 10mg prescription korea been made. Now how ought the father commands a putrefied that the city was left every one is a judge heaven and earth shall fail it appertains to condemn others. 24, p. Onaccoimt of these facts, it has been supp)osed that myxoedema isdue to a decrease or absence buy drug ultram 100mg in bangkok of the normal secretion of the thyroidgland, while exophthalmic goitre is due to an overproduction ofthe secretion of this gland. I would be a norwood class 3 with thinning sides, but the hair valium 10mg prescription korea on the back of my head is extremely thick. American thyroid association states that women are 5 to 10 times valium 10mg prescription korea more likely to develop hyperthyroidism than men. It is still undetermined how the diuresis is effected ; the increasein blood-pressure with dilatation of the renal vessels seems valium 10mg prescription korea sufficientto explain it in ordinary cases, but diuresis may occur without any rise ofpressure and also without dilatation of the vessels, and it has been ob-served in some valium 10mg prescription korea cases after a second injection which depressed the circula-tion rather than increased it. Tadalafil is> 10,000-fold more potent for pde5 than for pde3, an enzyme found in the heart and blood vessels.this selectivity for pde5 over pde3 is important because pde3 is an enzyme involved in cardiaccontractility. It seems likely that these symptoms are againthe result of the arsenic liberated from the atoxyl, and that they are differentfrom those ordinarily seen under arsenic, because the arsenic is liberated inunusual parts of the body, owing to the where to purchase alprazolam 1.5mg online in the uk atoxyl penetrating where the inorganicforms fail to reach.atoxyl, sodium arsanilate (cehynasoana), is a white crystalline powdercontaining 27.2 per cent, of arsenic metal, soluble in six parts of water or about125 parts of alcohol. Ron evans of thesalk institute, was based on the discovery of novel intracellularreceptors and their role in gene transcription, focusing on theidentification of agonists and antagonists, primarily of steroidhormone receptors. This body has also been called valium 10mg prescription korea epinephrine, siiprarenin,adrin, adnephrin, suprarenalin, etc., and has been purchase generic ultram with american express prepared by various firmsin standard solutions.group of lodothyrin.the valium 10mg prescription korea thyroid valium 10mg prescription korea gland of animals and its active principlelodothyrin produce marked changes in the metabolism.these consist of a great diminution of weight due to an buy lorazepam mesa increase inthe burning up of the body tissues; at first, of the fats alone, later, alsoof the proteids. It is knownthat food is allowed to pass through the pyloric sphincter only when thereaction is distinctly acid, and that the sphincter closes again when theduodenal mucous membrane is stimulated by acid; when the food inthe stomach is rendered strongly acid, it is found to leave the stomachmore slowly, though the movements of the organ appear, to be morerapid and stronger than normally.the acids are absorbed from the alimentary canal fairly rapidly inmost cases. The renal clearance of ciprofloxacin, which is approximately 300 ml/minute, exceeds the normal glomerular filtration rate of 120 ml/minute. However, a comparison of the quality of is phentermine a prescription drug datafrom a large number of clinical trials conducted across the globe revealed nosignificant differences in trial quality between different emerging and matureregions or countries [37]. Bentley continental gt online features and functionality at token rear seat arrangement (although.

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Age>65, hepatic impairment (e., cirrhosis), severe renal impairment (e., creatinine clearance<30 ml/min), and concomitant use of potent cytochrome p450 3a4 inhibitors (erythromycin),plasma levels of sildenafil at 24 hours post dose have been found to purchase diazepam 5mg online legit be valium 10mg prescription korea 3 to 8 times higher thanthose seen in healthy order diazepam 10mg in bangkok volunteers. The connection with DNA only helps to faster penetrate to the virus and destroy it on the stage of origin, and this gives more effective action during the treatment of herpes. These include hytrin® (terazosin hcl), flomax® (tamsulosin hcl), cardura® (doxazosin mesylate), minipress® (prazosin hcl) or uroxatral® (alfuzosin hcl). I start this process i might have to go through several surgeries and if i dona?t take propecia i can still look bald in time. Since the urine, aftertheir ingestion, does not check the growth of the gonococci, it isprobable that they do not produce their good effect by destroyingii1 62 local organic drugs.these bacteria, but valium 10mg prescription korea by preventing the decomposition of the urineremaining in contact with the diseased membrane and so decreasing the irritation and the lowering of the vitality of the tissueswhich would aflford a better field for the development of the disease. Thenerves to the sweat glands are anomalous in another feature for theirterminations are the only example in which atropine paralyzes sympa-thetic terminations.the secretion of the urine is often arrested immediately on theinjection of adrenaline and is then considerably augmented. The disc diffusion interpretive criteria valium 5mg prescription strength are provided in table 6. Oneshould be a bench-size lot and the other a where to purchase diazepam 5mg online europe larger, preferablyproduction-size, batch. Weight. It does not seem to be taken up fromthe skin, and has in fact little effect unless when rubbed on it, whenit ignites and gives rise to severe burns; phosphorus burns do notcause phosphorus poisoning, however, as is sometimes stated. Six-step survival guide for any woman who finds herself in a relationship with an impotent male. Drugs other than those listed here may also interact with sildenafil or affect your condition. Any material that comes into contact with thetest systems during the course of valium 10mg prescription korea the study should be free of valium 10mg prescription korea contaminants atlevels that would interfere with the study. (520 grains).salip3rrine, compound of salicylic acid and antip3rrine, white powdersoluble in about 200 parts water, very soluble in alcohol and chloroform.same action and uses as antipyrine.resop3rrine, compound of resorcine and antipyrine. Also, talk to your doctor about your complete medical history, especially if you have valium 10mg prescription korea heart problems such as angina (chest pain), heart failure, irregular heartbeat, or have had a heart attack or stroke. 6 marketing authorisation application (maa) valium 10mg prescription korea in the euwhen the cheap valium 10mg in bangkok data obtained from the clinical trials show that the drug under development is safe and efficacious in patients and that it can be manufactured withhigh quality, the drug development organisation may decide to seek marketingauthorisation [15]. A short overview with some examples and reference tothe relevant websites are given in table 3. Another sulphate preparation isthe liquor valium 10mg prescription korea ferri suhtmlphatis (u.), or monsel's solution, which is superfluousiron 649blaucts pills have in particular a well merited reputation in the treatmentof chlorosis and of chlorotic amenorrhea. Marked local irritation sometimes leading to vomiting and diarrhoea after internal administration. It is considered a good antidote for morphine on the centre of respiration.on account of its action on secretory nerves, it is used todecrease sweating in valium 10mg prescription korea phthisis or obesity, to decrease excessivesecretions of the bronchi in bronchorrhosa, before etherization tolessen salivation, and to stop the secretion of milk.it is used on account of its paralyzing action on the vagus incases of low pulse rate due to intracranial tumors or tumors of theneck pressing on this nerve. Each of these guidelinesaddresses the criteria of quality, safety or efficacy or a combination of these.some aspects of drug development, manufacture and control can be legallyenforced and are described in the us code of federal regulations [2] andeu legislation [3] such as good clinical practices (gcp) [4, 5], good manufacturing practices (gmp) [6] and good laboratory practices (glp) [7],national health authorities also issue guidelines local pharmaceutical industry is advised to follow if it wishes to obtain authorisation for manufacturingand commercialisation of the drug. Despite increasinguse of various kinds of alerting services and facilities, many ofthem computer-based, for retrieval or retrospective search ofpertinent information, personal perusal of cheap valium 5mg online in usa literature remainscritical, and the ability to initiate desktop searches is funda-mental to independent scientific research. They should receive an additional dose both during and at the end of dialysis.there are currently no dosing recommendations for pediatric patients with impairedrenal function. 145disappears. But with drugs like, it is now known that erectile dysfunction is largely a physical problem., erectile dysfunction was valium 10mg prescription korea treated with painful injections placed directly into the penis or sometimes with penile implants, which also would be invasive. V-medical is definitely tops among all the online pharmacies i have contacted. This it may do both by producing a dilatation of the splanchnic blood vessels and by decreasing the bulkof blood through watery evacuations.the use of purgatives is indicated valium 10mg prescription korea in all cases when the intestineis to be emptied, as after poisoning from drugs and from foodproducts, or when there is infection of the intestines, as in typhoidfever, or autointoxication due to fermentation or putrefactivechanges in valium 10mg prescription korea the intestinal contents.170 local organic drugs.they should not be used when there is severe inflammation of theintestines, and only with caution during pregnancy. In some organiza-tions, qa serves as the primary contact with regulatory agenciesand is the final authority for product acceptance (release) or re-jection. In the œtraditional approach of new drug development, humanpharmacokinetic data of a drug only become available after a phase 1 clinicaltrial is concluded. Depending upon the supersaturation (defined below) of the nonionized bases or acids valium 10mg prescription korea and thepresence of stabilizing agents, the resultant dispersions may bewithin the colloidal range. Thussyphilis and several of the exanthemata are generally acceptednot to recur valium 10mg prescription korea during the lifetime of an individual. Theyselect modes of distribution that will protect products fromadverse handling or environmental conditions while in transitto valium 10mg prescription korea distribution points and to customers. Forlocal analgesic effect menthol is especially applicable, and hasbeen used in the form of a stick rubbed over the temple and facefor neuralgia. Cheapest generic valium in london in this blinded crossover trial, 23 subjects with stable coronary artery disease valium 10mg prescription korea and evidence of exercise-induced cardiac ischemia were enrolled. Among these are skin eruptions of various1 for a detailed discussion of these principles see v. Nonclinical pharmacology, pharmacokinetics and toxicology data whenan application is made for the conduct of a fih clinical trial. In support valium 10mg prescription korea of such a combinationit has been foimd that the purchase generic diazepam in bangkok amount of chloroform present in ananaesthetized animal was much greater in the brain than in certain of buy diazepam online paypal the tissues, as the muscles, etc. If a man just had a fight with his wife and experienced ed for the first time resolving the tension in the relationship could likely fix the problem. Visual defects and cases of naion cheap diazepam in china have been reported in connection with the intake of andother pde5 inhibitors. Irritation of thestomach, or hyperacidity of the gastric juice, is, of course, a contra-indication.acid may also be used to make the urine acid, and thus to render itless favorable to the growth of microbes. Toronto’s core neighbourhoods have a legacy of valium 10mg prescription korea fine traditional styles that deserve a respectful and sensitive approach want to buy clonazepam 1mg in mexico when making improvements. The largest share of oppor-tunities is emerging in pharmaceutical applications, and this isexpected valium 10mg prescription korea to reach $18 billion in 2014.10the us national sciencefoundation predicts that nanotechnology will produce half of thepharmaceutical industry product line by 2015.11the old adage of the right drug for the right patient was tra-ditionally based on the trial and error method of matching pa-tients with the appropriate treatment protocol. Injecting prostaglandin, diazepam buy online australia a hormone-like stimulator produced in the body, induces erection. In mammalsthe usual symptoms arising from the action on the intestine and kidney areaccompanied by tremors and chorealike movements, later by tetanus, andfinally by valium 10mg prescription korea paralysis. valium 10mg prescription korea currently, many mabproducts are produced valium 10mg prescription korea by mammalian cell culture in which theproduct of interest valium 10mg prescription korea is expressed in large quantities.

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